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Phyllanthus, Phyllanthus amarus, Phyllanthus niruri, Phyllanthus urinaria

Proposed Uses: Chronic Hepatitis B

Hepatitis B is a two-stage illness. Its has an acute phase which causes jaundice, severe fatigue, and other symptoms. These symptoms usually resolve in a month or so; however, the infection may then become chronic. Long-term infection with hepatitis B can spread the disease to other people and can also lead to liver injury or liver cancer.

P. amarus has undergone considerable evaluation as a as a treatment for chronic hepatitis B, and a bit of study for acute hepatitis. However, the results have not been promising. The current consensus is that the herb is not helpful for hepatits. P. urinaria also appears to be ineffective.

Despite numerous test tube and animal studies showing efficacy against the hepatitis B virus,  P. amarus has generally not done well in human trials.

Dosage
The usual dose of P. amarus used in studies is 600 to 900 mg daily.

Safety Issues
There are no indications that P. amarus is toxic when used at recommended doses, but comprehensive safety studies have not been performed.  In double-blind studies, significant side effects have not been reported. Safety in pregnant or nursing women, or individuals with severe liver or kidney disease, has not been established.


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