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Mesoglycan; Aortic GAGs; Aortic Glycosaminoglycans; Chondroitin Polysulphate; Chondroitin Sulfate A; CSA; GAGs; Glycosaminoglycans; Mucopolysaccharide

Proposed Uses
  • Atherosclerosis; Intermittent Claudication; Varicose Veins
Other Proposed Uses
  • Hemorrhoids; High Cholesterol; Kidney Stones; Osteoarthritis; Phlebitis

Mesoglycan is found in many tissues, including the joints, intestines, and blood vessel linings. Related to the blood-thinning drug heparin and the supplement chondroitin, but unlike chondroitin, mesoglycan is primarily used to treat diseases of blood vessels.

For supplement purposes, mesoglycan is extracted from pig intestines. Very similar substances can be produced from cartilage, bone, and the lining of large blood vessels, and are often used interchangeably.

Therapeutic Dosages
The usual dosage of mesoglycan is 100 mg daily.

Several studies suggest that mesoglycan may be helpful in the treatment of vein problems, such as varicose veins/venous insufficiency, phlebitis, and hemorrhoids.

Safety Issues
Mesoglycan is essentially ground-up pig intestines and is believed to be safe, even if taken in large quantities. However, because mesoglycan appears to decrease blood clotting, it should not be combined with prescription blood thinners such as warfarin (Coumadin), clopidogrel (Plavix), ticlopidine (Ticlid), pentoxifylline (Trental), or heparin, or drugs in the aspirin family.


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