Corioulus versicolor
Trametes versicolor; Turkey Tail, Yun Zhi, Kawaratake
Proposed Uses: Cancer Treatment Support
Coriolus versicolor is a common tree fungus, rounded, horizontal protuberance from tree trunks. In traditional Chinese herbal medicine, this fungus is used to strengthen overall vitality and treat lung and liver problems as well as other conditions.
Currently, extracts of Coriolus versicolor called polysaccharide-K (PSK) and polysaccharopeptide (PSP) are under study as immune stimulants for use alongside chemotherapy in the treatment of cancer. According to most but not all reported trials, both PSK and PSP can enhance the effects of various forms of standard cancer treatment.
For example placebo-controlled study with advanced non–small-cell lung cancer, use of Coriolus extracts along with conventional treatment significantly slowed the progression of the disease. Very weak evidence hints that extracts of Coriolus versicolor might be helpful for HIV infection.
Dosage
A typical dosage of PSK or PSP as an adjunct to standard cancer treatment is 2 to 6 grams daily. For prevention of cancer, some experts recommend 500 mg daily, but there is no real scientific basis for this recommendation.
Safety Issues
PSP and PSK appear to be relatively nontoxic, both in the short and long term. Few side effects have been reported in clinical trials. However, safety in young children, pregnant or nursing women, or people with severe liver or kidney disease has not been established.
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