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Alzheimer's Supplements
Acetyl-L-carnitine
Ginkgo
Huperzine A
Phosphatidylserine
Vinpocetine
Carnosine
Citrulline
Choline or Phosphatidylcholine
DHEA
Lemon Balm
N-Acetylcysteine (NAC)
Sage

Citrulline; L-citrulline malate

Proposed Uses: Enhancing Sports Performance; Alzheimer’s Disease; Fatigue; Male Sexual Dysfunction (Impotence)

Citrulline is a non-essential amino acid, meaning that the body can manufacture it from other nutrients. Within the body, citrulline is converted to the amino acid L-arginine. Some of the proposed uses of citrulline supplements are based on raising levels of arginine. Citrulline also plays a role in a physiological process called “the urea cycle,” in which toxic ammonia is converted to urea.

Deficiency of citrulline is unlikely to occur.

Therapeutic Dosages
A typical dose of citrulline is 6–18 grams daily. It is commonly sold in the form of citrulline malate.

Therapeutic Uses
There is little scientific support for any use of citrulline supplements.
Citrulline is most commonly marketed today as a supplement for enhancing sports performance. Based on exceedingly speculative reasoning, it is often described as an aerobic complement to the supplement creatine. The only meaningful study reported thus far found that citrulline reduced rather than enhanced exercise capacity. Current enthusiasm for the supplement is therefore based entirely on testimonials.

Since placebos increase sense of energy and well-being, and may even enhance performance, enthusiastic testimonials about a new and exciting supplement should be received with considerable caution.

Safety Issues
As a naturally occurring amino acid, citrulline is believed to be safe. However, maximum safe doses in young children, pregnant or nursing women, or people with severe liver or kidney disease have not been established.

Feature Article

The Fountain of Youth?

What if I told you that it may be possible for you to live to age 100 or even longer, in better health than you are in right now? And, if you are already experiencing the ill effects of aging, what if I told you that it may be possible for you to look and feel 20 years younger and stay that way beyond the age of 100.

Aside from the fact that you'd probably call me crazy, I have to tell you that we have never been as close as we are today to actually being able to extend human life!

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